Behcet’s Disease – Endothelial Function

Endothelial cells form a multifunctional cell lining that covers all of the inner surface of blood vessels and regulates several important physiological and pathological reactions. These include inflammation/immune reaction, blood vessel tonus, hemostasis/thrombosis, angiogenesis and so on. Behçet’s Disease (BD) is a chronic, relapsing, multisystemic disorder characterized by urogenital ulcers and ocular inflammation with cutaneous, musculoskeletal, vascular and nervous system manifestations. People from the Far East, the Middle East and the Mediterranean basin are more commonly affected than those from other parts of the world. In Northern Europe, Central Africa and the United States the disease is infrequent. Affection for all ages with male predominance is a well-known clinical entity.